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Abiraterone/Niraparib Oral Tablet (NIRAPARIB/ABIRATERONE - ORAL)

For treating cancer.

Brand Name(s): Akeega

Generic Name: Abiraterone Acetate/Niraparib

Instructions

Swallow the medicine without crushing or chewing it.

Take the medicine on an empty stomach.

Do not eat for 2 hours before and 1 hour after taking this medicine.

Take the medicine with water.

This medicine will work best if you take it at about the same time every day.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember if it is on the same day. If you don’t remember until the next day, skip the missed dose and return to your regular schedule with the next dose. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

This medicine is not approved for use by women.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Men with a female partner who is of childbearing age must use reliable birth control during sexual activity while taking this medicine and for 4 months after stopping to prevent pregnancy.

Women who are pregnant or in their childbearing years should not touch or handle this medicine. This medicine can be absorbed through the woman's skin and harm the unborn baby.

Always carry an ID card or wear a medical alert bracelet indicating your medical condition.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • agitated feeling or trouble sleeping
  • constipation
  • nausea and vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • bleeding or bruising
  • chest pain
  • confusion
  • dizziness
  • swelling of the legs, feet, and hands
  • fainting
  • fever or chills
  • severe or persistent headache
  • fast or irregular heart beats
  • high blood pressure
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • muscle cramps or weakness
  • pale or blue skin, lips or fingernails
  • seizures
  • sore throat
  • unusual or unexplained tiredness or weakness
  • difficulty or discomfort urinating
  • blood in urine
  • blurring or changes of vision
  • unexpected or extreme weight loss

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.